Producers Resource Center

Aspirin Protects Against Colon Cancer

Colorectal is the second biggest cause of cancer death in the United States and Europe, where a total of 560,000 people develop the disease each year, and 250,000 die from it according to the American Association for Critical Illness insurance, the national trade organization.

Scientists at the Institute of Human Genetics at Newcastle University in Britain said the benefits of aspirin were only seen after several years.  The researchers noted that they uncovered a simple way of controlling stems cells that make tumors grow.

The researchers tested over 1,000 people with Lynch syndrome — an inherited condition that predisposes a person to a range of cancers, particularly of the colon.  Some were given aspirins and some a placebo.

Follow-up tests after 10 years showed that although there was no difference in cancer rates after 29 months, a significant difference was detected after four years.  Fewer people in the aspirin group developing colon cancer, the study’s leader noted.

To date, there have been only six colon cancers in the aspirin group as opposed to 16 who took placebo, the study notes.  There is also a reduction in endometrial cancer.

People with Lynch syndrome have an increased risk of many cancers including stomach, colon, brain, skin, and prostate. Women carriers also have a high risk of developing endometrial and ovarian cancers.

In low daily doses aspirin has been found to stave off the risk of heart attacks and strokes, as well as chase away occasional aches and pains.  Other scientists have previously found it can reduce the risk of developing colon cancer and suggested it does so by blocking the enzyme cyclooxygenase2, or COX-2, which promotes inflammation and cell division and is found in high levels in tumors.

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