Producers Resource Center

More Proof That Statins Cut Stroke Risk

Each year about 600,000 Americans experience their first stroke and 185,000 have a recurrent stroke, according to the American Association for Critical Illness Insurance.  African Americans have almost twice the risk of first-ever stroke compared with white adults. 

Researchers found that much of the benefit from statins such as Crestor, Lipitor and Zocor appears tied to the drugs’ lowering of blood levels of “bad” LDL cholesterol.  Their review of data from clinical trials including almost 267,000 participants showed an overall 12 percent reduction in stroke incidence among those taking statins, with each 1 percent reduction in total cholesterol predicting a 0.8 percent relative risk reduction of stroke. 

Medical experts note that the report contains hints that the reduction of stroke risk is not entirely explained by the cholesterol-lowering effect of statins.  They noted that there are many possible explanations for the reduction in stroke risk observed in actively treated patients, and one of those is a reduction of inflammation with statin therapy. 

There was no debate about the value of statin therapy in reducing other cardiovascular risks in people with high LDL levels. The Italian analysis found more benefits from statins than from other cholesterol-lowering regimens. 

The most gratifying thing reported by this meta-analysis is that statins among all lipid-lowering therapies appear to be the most effective, noted an expert from the Mayo Clinic in Minnesota. The use of statin therapy is particularly important among people who have had a stroke. They are being used more aggressively in people who have had a stroke in an attempt to prevent another. 

At least one trial has shown a significant reduction in second strokes among people taking statins.  The report, published in the Jan. 19 issue of the Journal of the American College of Cardiology, was led by physicians at G. d’Annunzio University in Chieti, Italy.

Share and Enjoy:
  • Print this article!
  • Digg
  • del.icio.us
  • Facebook
  • Google Bookmarks
  • Reddit
  • Slashdot
  • StumbleUpon
  • Twitter
  • LinkedIn

Tags: , , , , , , , , ,