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Protein May Identify Breast Cancer

German researchers have identified a protein linked to more aggressive and advanced breast cancer tumors.

The scientists studied samples of breast tissue from patients with cancer and compared them with healthy breast tissue.  Researchers found that those whose tumors had elevated levels of GLI1 (glioma-associated oncogene homolog 1) protein tended to have a more advanced stage of cancer, had an increased number of cancerous lymph nodes and a greater chance of death.

Measurement of GLI1 could be a useful for determining cancer prognosis, according to the study which is published this week in the journal BMC Cancer.

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