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Protein May Predict Heart Attack

According to a study published in the medical journal of the American Academy of Neurology the C-reactive protein (CRP), a marker for inflammation in the blood, may predict those at higher risk for heart attack and death but not stroke. 

The study involved over 2,200 people who were 40 years old or older and stroke-free.  All participants had their blood tested for CRP levels and were evaluated for stroke and heart attack risk factors. 

Participants were followed for an average of eight years. In that time, there were 198 strokes, 156 heart-related events and 586 deaths.  The group was comprised of 63 percent Hispanic, 20 percent non-Hispanic black and 15 percent non-Hispanic white residents. 

The study’s researchers found that people with CRP levels greater than three milligrams per liter were 70 percent more likely to suffer a heart attack and 55 percent more likely to die early compared to people who had levels of one milligram per liter or less of the protein in their blood. The protein was not associated with an increased risk of stroke once other risk factors were taken into account.

Prior studies have found the C-reactive protein to be a marker for predicting risk of heart disease.  CRP protein levels are associated with such medical and lifestyle risk factors as diabetes, smoking, alcohol consumption and physical activity.   A lead researcher noted that by living a healthy lifestyle, one may be able to lower these protein levels, thus lowering the risk of cardiac events and possibly early death.   The study was supported by the National Institutes of Health.

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