Posts Tagged ‘obsesity’

Diabetes Drug May Also Help With Weight Loss

Sunday, October 25th, 2009

Medical researchers reported that three-quarters of patients on high doses of the drug liraglutide lost 5% or more of their body weight.  The medication is used for the treatment of type 2 diabetes.  It was approved earlier this year in Europe for the treatment of diabetes and is marketed under the brand name Victoza.

The injected drug stimulates the release of insulin when glucose levels become too high. It also helps curb appetite. In a new study, researchers in Denmark assigned obese people to one of four liraglutide doses, a placebo or the weight-loss drug orlistat. All the participants followed a diet of about 500 fewer calories than they needed to maintain their weight. They also increased their physical activity levels.

After 20 weeks, those on the medication liraglutide lost more weight than those on the placebo.  Participants on the highest dose of the medication lost 15 pounds, compared with 6 pounds on the placebo and 9 pounds on orlistat. Three-quarters of the subjects on the highest dosage of lost 5% or more of their body weight.

Researchers reported that the medication also reduced blood pressure. At the three highest dosages, reduced symptoms of pre-diabetes, blood glucose levels above normal but not yet high enough to qualify as diabetes.
The study was funded by Novo Nordisk, the Denmark-based company that makes Victoza.